Nattokinase is an enzyme supplement that has become popular among South Africans exploring traditional Japanese wellness foods. This guide explains what it is and what to look for. It is general information, not medical advice — nattokinase can affect blood clotting, so speak to your doctor before using it, particularly if you take blood-thinning medication.
What is nattokinase?
Nattokinase is an enzyme extracted from natto, a traditional Japanese food made from fermented soybeans. The fermentation uses a bacterium called Bacillus subtilis natto, which produces the nattokinase enzyme. In supplement form it is separated from the natto and supplied as capsules, so you get the enzyme without natto’s famously strong taste and smell.
How it is used
Nattokinase is usually taken as a daily capsule, often on an empty stomach. Strength is measured in fibrinolytic units, shown on labels as FU — a 2,000 FU serving is a common standard. People take it as part of a general wellness routine.
What to look for
- FU strength: look for the fibrinolytic units per serving (e.g. 2,000 FU).
- Vitamin K2 content: some nattokinase is “K2-free” or standardised — relevant if you take medication affected by vitamin K.
- Quality sourcing: choose a reputable brand with clear labelling.
Important safety note
Because nattokinase may influence blood clotting, it is not suitable for everyone — especially people on anticoagulants, those with bleeding disorders, anyone due for surgery, or who are pregnant or breastfeeding. Always check with a healthcare professional first.
Frequently asked questions
What does FU mean?
Fibrinolytic units — the standard measure of nattokinase activity and strength.
Is nattokinase vegan?
It is derived from fermented soy, and many products use vegetarian capsules — check the label for confirmation.
Does it smell like natto?
No — the isolated enzyme in capsules does not carry natto’s strong aroma.
Where to buy nattokinase in South Africa
At Anadea you can buy nattokinase supplements from trusted natural-health brands, in stock with fast nationwide delivery. Browse our enzyme range to find a strength that fits your routine.